Archives of Medical Research
Volume 37, Issue 7 , Pages 899-902 , October 2006

Epidemiology of Adverse Cutaneous Drug Reactions. A Prospective Study in Hospitalized Patients

  • Amparo Hernandez-Salazar

      Affiliations

    • Department of Dermatology Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico City, Mexico
    • ,
  • Samuel Ponce de Leon-Rosales

      Affiliations

    • Subdivision of Hospital Epidemiology and Patient Care Quality Control Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico City, Mexico
    • ,
  • Sigfrido Rangel-Frausto

      Affiliations

    • Pharmacy Department, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico City, Mexico
    • ,
  • Elia Criollo

      Affiliations

    • Pharmacy Department, Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico City, Mexico
    • ,
  • Carla Archer-Dubon

      Affiliations

    • Department of Dermatology Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico City, Mexico
    • ,
  • Rocio Orozco-Topete

      Affiliations

    • Department of Dermatology Instituto Nacional de Ciencias Médicas y Nutrición, Salvador Zubirán, Mexico City, Mexico
    • Corresponding Author InformationAddress reprint requests to: Rocio Orozco-Topete, MD, Dermatology Department, Vasco de Quiroga 15, sección XVI, Tlalpan, 14000, México, D.F., México

Received 2 June 2005 ,Accepted 20 March 2006.

References 

  1. Ives TJ, Bentz EJ, Gwyther RE. Drug-related admissions to a family medicine inpatient service. Arch Intern Med. 1987;147:1117–1120
  2. Stern RS, Steinberg L. Epidemiology of adverse cutaneous reactions to drugs. Dermatol Clin. 1995;13:681–688
  3. Naldi L, Conforti A, Venegoni M, Troncon MG, Caputi A, Ghiotto E, et al. Cutaneous reactions to drugs. An analysis of spontaneous reports in four Italian regions. Br J Clin Pharmacol. 1999;48:839–846
  4. Arndt KA, Jick H. Rates of cutaneous reactions to drugs. A report from the Boston Collaborative Drug Surveillance Program. JAMA. 1976;235:918–923
  5. Bigby M, Jick S, Jick H, Arndt K. Drug-induced cutaneous reactions. A report from the Boston Collaborative Drug Surveillance Program on 15,438 consecutive inpatients, 1975–1982. JAMA. 1986;256:3358–3363
  6. Hunziker T, Kunzi UP, Braunschweig S, Zehnder D, Hoigne R. Comprehensive hospital drug monitoring (CHDM): adverse skin reactions, a 20 year survey. Allergy. 1997;52:388–393
  7. Fiszenson-Albala F, Auzerie V, Mahe E, Farinotti R, Durand-Stocco C, Crickx B, et al. A 6-month prospective survey of cutaneous drug reactions in a hospital setting. Br J Dermatol. 2003;149:1018–1022
  8. Bégaud B. Imputabilité des effets inattendus ou toxiques des medicaments. Thérapie. 1985;40:111–118
  9. Faich GA. Special Report: Adverse drug reaction monitoring. N Engl J Med. 1986;314:1589–1592
  10. de Shazo RD, Kemp SF. Allergic reactions to drugs and biologic agents. JAMA. 1997;278:1875–1906
  11. Schmitt LC. Drug reactions in the elderly. Cutis. 1988;41:58–60
  12. Roujeau JC, Bioulac-Sage P, Bourseau C, Guillaume JC, Bernard P, Lok C, et al. Acute generalized exanthematous pustulosis. Arch Dermatol. 1991;127:1333–1338
  13. Sawhney RA, Dubin D, Otley CC. Generalized exanthematous pustulosis induced by medications. Int J Dermatol. 1996;35:826–827
  14. Knowless SR, Shapiro LE, Shear NH. Anticonvulsant hypersensitivity syndrome: incidence, prevention and management. Drug Saf. 1999;21:489–501
  15. De Vriese SP, Phillipe J, Van Renterghem DM, et al. Carbamazepine hypersensitivity syndrome: report of 4 cases and review of the literature. Medicine. 1995;74:144–151
  16. Roujeau JC, Stern RS. Severe adverse cutaneous reactions to drugs. N Engl J Med. 1994;331:1272–1284
  17. Rzany B, Correia O, Kelly JP, et al. for the Study Group of the International Case Control Study on Severe Cutaneous Adverse Reactions Risk of Stevens-Johnson syndrome and toxic epidermal necrolysis during the first week of antiepileptic therapy: a case-control study. Lancet. 1999;353:2190–2194
  18. Avakian R, Flowers FP, Araujo OE, Ramos-Caro FA. Toxic epidermal necrolysis: a review. J Am Acad Dermatol. 1991;25:69–79
  19. Yamamura S, Arai K, Toyabe S, et al. Simultaneous activation of granulocytes and extrathymic T cells in number and function by excessive administration of nonsteroidal anti-inflammatory drugs. Cell Immunol. 1996;173:303–311
  20. Rubin RL, Kretz-Rommel A. Phagocyte-mediated oxidation in idiosyncratic adverse drug reactions. Curr Opin Hematol. 2001;8:34–40
  21. Coopman SA, Stern SR. Cutaneous drug reactions in human immunodeficiency virus infection. Arch Dermatol. 1991;127:714–717
  22. Stern RS. Epidemiology of skin disease in HIV infection: a cohort study of health maintenance. J Invest Dermatol. 1994;102:345–375
  23. Crowson AN, Magro CM. Recent advances in the pathology of cutaneous drug eruptions. Dermatol Clin. 1999;17:537–560
  24. García-Doval I, Le Cleach L, Bocquet H, et al. Toxic epidermal necrolysis and Stevens–Johnson syndrome. Does early withdrawal of causative drugs decrease the risk of death?. Arch Dermatol. 2000;136:323–327

PII: S0188-4409(06)00168-8

doi: 10.1016/j.arcmed.2006.03.010

Archives of Medical Research
Volume 37, Issue 7 , Pages 899-902 , October 2006

Article Tools