Archives of Medical Research
Volume 37, Issue 8 , Pages 1034-1037 , November 2006

Blood Coagulation Unaffected by Ozonated Autohemotherapy in Patients on Maintenance Hemodialysis

  • Bogdan Biedunkiewicz

      Affiliations

    • Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    • Corresponding Author InformationAddress reprint requests to: Bogdan Biedunkiewicz, MD, PhD, Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, ul. Debinki 7, 7, 80-211 Gdansk, Poland
    • ,
  • Slawomir Lizakowski

      Affiliations

    • Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    • ,
  • Leszek Tylicki

      Affiliations

    • Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    • ,
  • Anna Skiboeska

      Affiliations

    • Department of Clinical Biochemistry, Medical University of Gdansk, Gdansk, Poland
    • ,
  • Tomas Nieweglowski

      Affiliations

    • Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    • ,
  • Andrzej Chamienia

      Affiliations

    • Independent Unit of General Nursing, Medical University of Gdansk, Gdansk, Poland
    • ,
  • Alicja Debska-Slizien

      Affiliations

    • Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland
    • ,
  • Boleslaw Rutkowski

      Affiliations

    • Department of Nephrology, Transplantology and Internal Medicine, Medical University of Gdansk, Gdansk, Poland

Received 11 May 2006 ,Accepted 28 June 2006.

References 

  1. Di Paolo N, Bocci V, Gaggiotti E. Ozone therapy. Int J Artif Organs. 2004;27:168–175
  2. Sroczynski J, Antoszewski Z, Matyszczyk B, Krupa G, Rudzki H, Zbronska H, et al. Clinical assessment of treatment results for atherosclerotic ischemia of the lower extremities with intraarterial ozone injections. Pol Tyg Lek. 1992;47:964–966
  3. Tylicki L, Nieweglowski T, Biedunkiewicz B, Burakowski S, Rutkowski B. Beneficial clinical effects of ozonated autohemotherapy in chronically dialysed patients with atherosclerotic ischemia of the lower limbs–pilot study. Int J Artif Organs. 2001;24:79–82
  4. Biedunkiewicz B, Tylicki L, Nieweglowski T, Burakowski S, Rutkowski B. Clinical efficacy of ozonated autohemotherapy in hemodialyzed patients with intermittent claudication: an oxygen controlled study. Int J Artif Organs. 2004;27:29–34
  5. Biedunkiewicz B, Tylicki L, Lichodziejewska-Niemierko M, Liberek T, Rutkowski B. Ozonetherapy in a dialyzed patient with calcific uremic arteriolopathy. Kidney Int. 2003;64:367–368
  6. Wilhelmsen L, Svardsudd K, Korsan-Bengtsen K, Larsson B, Welin L, Tibblin G. Fibrinogen as a risk factor for stroke and myocardial infarction. N Engl J Med. 1984;311:501–505
  7. Lowe GD, Fowkes FG, Dawes J, Donnan PT, Lennie SE, Housley E. Blood viscosity, fibrinogen, and activation of coagulation and leukocytes in peripheral arterial disease and the normal population in the Edinburgh Artery Study. Circulation. 1993;87:1915–1920
  8. Smith FB, Rumley A, Lee AJ, Leng GC, Fowkes FG, Lowe GD. Haemostatic factors and prediction of ischaemic heart disease and stroke in claudicants. Br J Haematol. 1998;100:758–763
  9. Rosc D, Ponikowska I, Paczuski R, Wlodarczyk K, Zastawna E, Michalski A. The influence of ozone therapy on endothelial damage markers in patients with atherosclerosis of lower extremities. Pol Merkuriusz Lek. 1999;6:135–137
  10. Ambuhl PM, Wuthrich RP, Korte W, Schmid L, Krapf R. Plasma hypercoagulability in haemodialysis patients: impact of dialysis and anticoagulation. Nephrol Dial Transplant. 1997;12:2355–2364
  11. Giunta R, Coppola A, Luongo C, Sammartino A, Guastafierro S, Grassia A, et al. Ozonized autohemotransfusion improves hemorheological parameters and oxygen delivery to tissues in patients with peripheral occlusive arterial disease. Ann Hematol. 2001;80:745–748
  12. Sroczynski J, Antoszewski Z, Krupa G, Zbronska H, Matyszczak B, Rudzki H, et al. Some hemostatic parameters after treatment with ozone in a group of patients with obliterative atherosclerosis of the lower extremities and in a group of patients with diabetes. Pol Tyg Lek. 1991;46:694–696
  13. Maslennikov O, Sharov I, Potekhina I, Dushkina N, Kryzhanovskaia N, Maslennikova N, et al. Effect of ozone therapy on hemostatic changes in patients with vascular atherosclerosis. Klin Med (Mosk). 1997;10:35–37
  14. Bocci V. Biological and clinical effects of ozone. Has ozone therapy a future in medicine?. Br J Biomed Sci. 1999;56:270–279
  15. Bocci V. Oxygen-Ozone Therapy. A Critical Evaluation. Dordrecht: Kluwer Academic Publishers; 2002;
  16. Tylicki L, Nieweglowski T, Biedunkiewicz B, Chamienia A, Debska-Slizien A, Aleksandrowicz E, et al. The influence of ozonated autohemotherapy on oxidative stress in hemodialyzed patients with atherosclerotic ischemia of lower limbs. Int J Artif Organs. 2003;26:297–303
  17. Tylicki L, Biedunkiewicz B, Nieweglowski T, Grabowska M, Chamienia A, Slizien AD, et al. Fistula function and dialysis adequacy during ozonotherapy in chronically hemodialyzed patients. Artif Organs. 2004;28:513–517
  18. Biedunkiewicz B, Tylicki L, Rachon D, Hak L, Nieweglowski T, Chamienia A, et al. Natural killer cell activity unaffected by ozonated autohemotherapy in patients with end-stage renal disease on maintenance renal replacement therapy. Int J Artif Organs. 2004;27:766–771
  19. Tylicki L, Biedunkiewicz B, Rachon D, Nieweglowski T, Hak L, Chamienia A, et al. No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients. Mediators Inflamm. 2004;13:377–380
  20. Tylicki L, Lizakowski S, Biedunkiewicz B, Skibowska A, Nieweglowski T, Chamienia A, et al. Platelet function unaffected by ozonated autohaemotherapy in chronically haemodialysed patients. Blood Coagul Fibrinolysis. 2004;15:619–622
  21. Coppola L, Lettieri B, Cozzolino D, Luongo C, Sammartino A, Guastafierro S, et al. Ozonized autohaemotransfusion and fibrinolytic balance in peripheral arterial occlusive disease. Blood Coagul Fibrinolysis. 2002;13:671–681

PII: S0188-4409(06)00223-2

doi: 10.1016/j.arcmed.2006.06.006

Archives of Medical Research
Volume 37, Issue 8 , Pages 1034-1037 , November 2006

Article Tools