Archives of Medical Research
Volume 38, Issue 7 , Pages 752-756 , October 2007

Depressive Symptoms and Hypomagnesemia in Older Diabetic Subjects

  • Lázaro Barragan-Rodríguez

      Affiliations

    • Medical Research Unit in Clinical Epidemiology, Mexican Social Security Institute (IMSS), Durango, Mexico
    • Research Group on Diabetes and Chronic Illnesses, Durango, Mexico
    • ,
  • Martha Rodríguez-Morán

      Affiliations

    • Medical Research Unit in Clinical Epidemiology, Mexican Social Security Institute (IMSS), Durango, Mexico
    • Research Group on Diabetes and Chronic Illnesses, Durango, Mexico
    • ,
  • Fernando Guerrero-Romero

      Affiliations

    • Medical Research Unit in Clinical Epidemiology, Mexican Social Security Institute (IMSS), Durango, Mexico
    • Research Group on Diabetes and Chronic Illnesses, Durango, Mexico
    • Corresponding Author InformationAddress reprint requests to: Fernando Guerrero-Romero, MD, PhD, FACP, Siqueiros 225 esq./Castañeda, 34000 Durango, Dgo., Mexico

Received 22 December 2006 ,Accepted 14 March 2007.

References 

  1. Muller-Spahn F, Hock C. Clinical presentation of depression in the elderly. Gerontology. 1994;40(Suppl 1):10–14
  2. Tellez-Zenteno JF, Cardiel MH. Risk factors associated with depression in patients with type 2 diabetes mellitus. Arch Med Res. 2002;33:53–60
  3. Lopez Martinez J, Sanchez Castilla M, Garcia de Lorenzo y Mateos A, Culebras Fernandez JM. Magnesium: metabolism and requirements. Nutr Hosp. 1997;2:4–14
  4. Tosiello L. Hypomagnesemia and diabetes mellitus. A review of clinical implications. Arch Intern Med. 1996;156:1143–1147
  5. Elin RJ. Magnesium metabolism in health and disease. Dis Mon. 1988;34:161–218
  6. Guerrero-Romero F, Rodríguez-Morán M. Complementary therapies for diabetes: the case for chromium, magnesium, and antioxidants. Arch Med Res. 2005;36:250–257
  7. Lefebvre PJ, Paolisso G, Scheen AJ. Magnesium and glucose metabolism. Therapie. 1994;49:1–7
  8. Vaquero MP. Magnesium and trace elements in the elderly: intake, status and recommendations. J Nutr Health Aging. 2002;6:147–153
  9. Levin GE, Mather HM, Pilkington TR. Tissue magnesium status in diabetes mellitus. Diabetologia. 1981;21:131–134
  10. Gums JG. Magnesium in cardiovascular and other disorders. Am J Health Syst Pharm. 2004;61:1569–1576
  11. Guerrero-Romero F, Tamez-Perez HE, González-González G, Salinas-Martinez AM, Montes-Villareal J, Treviño-Ortiz JH, et al. Oral magnesium supplementation improves insulin sensitivity in non-diabetic subjects with insulin resistance. A double-blind placebo-controlled randomized trial. Diabetes Metab. 2004;30:253–258
  12. Rasmussen HH, Mortensen PB, Jensen IW. Depression and magnesium deficiency. Int J Psychiatry Med. 1989;19:57–63
  13. Kirov GK, Birch NJ, Steadman P, Ramsey RG. Plasma magnesium levels in a population of psychiatric patients: correlations with symptoms. Neuropsychobiology. 1994;30:73–78
  14. Black SA. Increased health burden associated with comorbid depression in older diabetic Mexican Americans. Diabetes Care. 1999;22:56–64
  15. Touitou Y, Godard JP, Ferment O, Chastang C, Proust J, Bogdan A, et al. Prevalence of magnesium and potassium deficiencies in the elderly. Clin Chem. 1987;33:518–523
  16. Banki CM, Vojnik M, Papp Z, Balla KZ, Arato M. Cerebrospinal fluid magnesium and calcium related to amine metabolites, diagnosis, and suicide attempts. Biol Psychiatry. 1985;20:163–171
  17. Levine J, Stein D, Rapaport A, Kurtzman L. High serum and cerebrospinal fluid Ca/Mg ratio in recently hospitalized acutely depressed patients. Neuropsychobiology. 1999;39:63–70
  18. Santillana SP, Alvarado LE. Depresión en población adulta mayor: tamizaje en unidad de primer nivel de atención médica. Rev Med IMSS. 1999;37:111–115
  19. Rodríguez-Morán M, Guerrero-Romero F. Oral magnesium supplementation improves insulin sensitivity and metabolic control in Type 2 diabetic subjects. A randomized, double-blind controlled trial. Diabetes Care. 2003;26:1147–1152
  20. Report of the Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. Diabetes Care. 2000;23(Suppl 1):S4–S19
  21. Anderson RJ, Freedland KE, Clouse RE, Lustman PJ. The prevalence of comorbid depression in adults with diabetes: a meta-analysis. Diabetes Care. 2001;24:1069–1078
  22. Ciechanowski PS, Katon WJ, Russo JE. Depression and diabetes: impact of depressive symptoms on adherence, function, and costs. Arch Intern Med. 2000;160:3285
  23. Benton D, Donohoe RT. The effects of nutrients on mood. Public Health Nutr. 1999;2:403–409
  24. Banki CM, Arato M, Kilts CD. Aminergic studies and cerebrospinal fluid cations in suicide. Ann NY Acad Sci. 1986;487:221–230
  25. Williams WA, Shoaf SE, Hommer D, Rawlings R, Linnoila M. Effects of acute tryptophan depletion on plasma and cerebrospinal fluid tryptophan and 5-hydroxyindoleacetic acid in normal volunteers. J Neurochem. 1999;72:1641–1647
  26. Mitani H, Shirayama Y, Yamada T, Kawahara R. Plasma levels of homovanillic acid, 5-hydroxyindoleacetic acid and cortisol, and serotonin turnover in depressed patients. Prog Neuropsychopharmacol Biol Psychiatry. 2006;30:531–534
  27. Stuerenburg HJ, Ganzer S, Muller-Thomsen T. 5-Hydroxyindoleacetic acid and homovanillic acid concentrations in cerebrospinal fluid in patients with Alzheimer's disease, depression and mild cognitive impairment. Neuro Endocrinol Lett. 2004;25:435–437
  28. Suarez EC. Relations of trait depression and anxiety to low lipid and lipoprotein concentrations in healthy young adult women. Psychosom Med. 1999;61:273–279
  29. Corica F, Corsonello A, Ientile R, Cucinotta D, Di Benedetto A, Perticone F, et al Serum ionized magnesium levels in relation to metabolic syndrome in type 2 diabetic patients. J Am Coll Nutr. 2006;25:210–215
  30. Biondi B, Palmieri EA, Klain M, Schlumberger M, Filetti S, Lombardi G. Subclinical hyperthyroidism: clinical features and treatment options. Eur J Endocrinol. 2005;152:1–9
  31. Caparevic Z, Stojanovic D, Ilic V, Bojkovic G, Stojanovic M. Lipid abnormalities in elderly patients with subclinical hyperthyroidism. Med Pregl. 2003;56:564–567
  32. Gilroy CV, Horney BS, Burton SA, MacKenzie AL. Evaluation of ionized and total serum magnesium concentrations in hyperthyroid cats. Can J Vet Res. 2006;70:137–142

PII: S0188-4409(07)00125-7

doi: 10.1016/j.arcmed.2007.03.008

Archives of Medical Research
Volume 38, Issue 7 , Pages 752-756 , October 2007

Article Tools