Archives of Medical Research
Volume 39, Issue 5 , Pages 483-488 , July 2008

Anti-arrhythmic Effects of κ-Opioid Receptor and Its Changes in Ischemia and Reperfusion

  • Liu Jin-Cheng

      Affiliations

    • Department of Physiology, National Key Discipline of Cell Biology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • Department of Cardiac Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Yin Wen

      Affiliations

    • Department of Emergency, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Yin Zhao

      Affiliations

    • Department of Physiology, National Key Discipline of Cell Biology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Zhang Quan-Yu

      Affiliations

    • Department of Physiology, National Key Discipline of Cell Biology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Zhang Shu-Miao

      Affiliations

    • Department of Physiology, National Key Discipline of Cell Biology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Guo Hai-Tao

      Affiliations

    • Department of Physiology, National Key Discipline of Cell Biology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Bi Hui

      Affiliations

    • Department of Physiology, National Key Discipline of Cell Biology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Wang Yue-Min

      Affiliations

    • Department of Physiology, National Key Discipline of Cell Biology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Sun Xin

      Affiliations

    • Department of Physiology, National Key Discipline of Cell Biology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Cheng Liang

      Affiliations

    • Department of Cardiac Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Cui Qin

      Affiliations

    • Department of Cardiac Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Yu Shi-Qiang

      Affiliations

    • Department of Cardiac Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Alan Kaye

      Affiliations

    • Department of Anesthesiology and Department of Pharmacology, LSU School of Medicine, New Orleans, Louisiana
    • ,
  • Yi Ding-Hua

      Affiliations

    • Department of Cardiac Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • ,
  • Pei Jian-Ming

      Affiliations

    • Department of Physiology, National Key Discipline of Cell Biology, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • Department of Cardiac Surgery, Xijing Hospital, Fourth Military Medical University, Xi'an, Shaanxi Province, China
    • Corresponding Author InformationAddress reprint requests to: Pei Jian-Ming, Fourth Military Medical University, Department of Physiology, No.169, West Changle Road, Xi'an, Shaanxi Province 710032; China

Received 5 January 2008 ,Accepted 21 February 2008.

References 

  1. Cheng L, Ma S, Wei LX, Guo HT, Huang LY, Bi H, et al. Cardioprotective and anti-arrhythmic effect of U50,488H in ischemia/reperfusion rat heart. Heart Vessels. 2007;22:335–344
  2. Fang X, Tang W, Sun S, Weil MH. δ-Opioid-induced pharmacologic myocardial hibernation during cardiopulmonary resuscitation. Crit Care Med. 2006;34:S486–S489
  3. Lishmanov AI, Lasukova TV, Maslov LN, Platonov AA. Role of kappa-opioid receptors in the regulation of cardiac resistance to arrhythmogenic effects of ischemia and reperfusion. Ross Fiziol Zh Im I M Sechenova. 2006;92:1419–1428
  4. Giros B, Pohl M, Rochelle JM, Seldin MF. Chromosomal localization of opioid peptide and receptor genes in the mouse. Life Sci. 1995;56:PL369–PL375
  5. Walker MJ, Curtis MJ, Hearse DJ, Campbell RW, Janse MJ, Yellon DM, et al. The Lambeth conventions: guidelines for the study of arrhythmias in ischaemia infarction, and reperfusion. Cardiovasc Res. 1988;22:447–455
  6. Ras M, Girbal-Neuhauser E, Paul E, Spérandio M, Lefebvre D. Protein extraction from activated sludge: an analytical approach. Water Res. 2008;42:1867–1878
  7. Zhang P, Zhu YL, Wang YM, Li MZ, Bi H, Pei JM. Impact of specific κ-OR excitomotor U50,488H on ventricular arrhythmia which is induced by ischemia/reperfusion. J Fourth Military Medical University. 2004;25:1648–1651
  8. Yao Q, Wang YM, Zhang P, Bi H, Pei JM. Anti-arrhythmia effect of κ opioid receptor. Chinese J Heart. 2004;16:109–112
  9. Ma S, Ma JX, Lv SY, Wang YM, Pei JM. Impact of opioid on arrhythmia and mechanisms. J Zhong Guo Shi Yong Yi Xue Yan Jiu. 2005;4:174–177
  10. Peart JN, Gross ER, Gross GJ. Effect of exogenous kappa opioid receptor activation in rat model of myocardial infarction. J Cardiovasc Pharmacol. 2004;43:410–415
  11. Boutin H, Catherine A, Mackenzie ET, Jauzac P, Dauphin F. Long-term alterations in mu, delta and kappa opioidergic receptors following middle cerebral artery occlusion in mice. Acta Neuropathol (Berl). 2007;114:491–500
  12. Xia Q, Zhang WM, Shen YL, Wong TM. Decreased affinity of κ-receptor binding during reperfusion following ischaemic preconditioning in the rat heart. Life Sci. 1996;58(16):1307–1313

PII: S0188-4409(08)00104-5

doi: 10.1016/j.arcmed.2008.02.011

Archives of Medical Research
Volume 39, Issue 5 , Pages 483-488 , July 2008

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