Archives of Medical Research
Volume 41, Issue 1 , Pages 14-18 , January 2010

Diagnostic Value of Adenosine Deaminase Activity in Benign and Malignant Breast Tumors

  • Mahmoud Aghaei

      Affiliations

    • Department of Clinical Biochemistry, Cancer Research Laboratory, School of Medical Sciences, Tarbiat Modarres University, Tehran, Iran
  • ,
  • Fatemeh Karami-Tehrani

      Affiliations

    • Department of Clinical Biochemistry, Cancer Research Laboratory, School of Medical Sciences, Tarbiat Modarres University, Tehran, Iran
    • Corresponding Author InformationAddress reprint requests to: F. Karami-Tehrani, Ph.D., Clinical Biochemistry Department, School of Medical Sciences, Tarbiat Modarres University, P.O. Box: 14115-331, Tehran, Iran; Phone: +98 (21) 88011001 (ext. 3567); FAX: +98 (21) 82884555
  • ,
  • Siamak Salami

      Affiliations

    • Department of Biochemistry, School of Medical Science, Urmia University of Medical Sciences, Urmia, Iran
  • ,
  • Morteza Atri

      Affiliations

    • Department of Surgery, School of Medical Science, Tehran University of Medical Science, Tehran, Iran

Received 19 July 2009 ,Accepted 22 October 2009.

References 

  1. McPherson K, Steel CM, Dixon JM. ABC of the breast disease, breast caner epidemiology, risk factors, and genetics. Br Med J. 2000;321:624–628
  2. Lizuka H, Koizumi H, Kamikagi K, et al. Two forms of adenosine deaminase in pig epidermis. J Dermatol. 1981;18:91–95
  3. Stancikova M, Lukac J, Istok R, et al. Serum adenosine deaminase activity and its isoensyme pattern in patients with systemic lupus erythematosus. Clin Exp Rheumatol. 1998;16:583–586
  4. Ratech H, Martiniuk F, Borer WZ, et al. Differential expression of adenosine deaminase isoenzymes in acute leukemia. Blood. 1988;72:1627–1632
  5. Zukkerman SH, Olson JM, Douglas SD. Adenosine deaminase activity during in vitro culture of human peripheral blood monocytes and pulmonary alveolar macrophage. Exp Cell Res. 1980;129:281–287
  6. Gakis C. Adenosine deaminase (ADA) isoenzymes ADA1 and ADA2: diagnostic and biological role. Eur Respir J. 1996;9:623–624
  7. Aghaei M, Karami-Tehrani F, Salami S, et al. Adenosine deaminase activity in the serum and malignant tumors of breast cancer: The assessment of isoenzyme ADA1 and ADA2 activities. Clin Biochem. 2005;38:887–891
  8. Walia M, Mahajan M, Singh K. Serum adenosine deaminase, 5′-nucleotidase and alkaline phosphates in breast cancer patients. Indian J Med Res. 1995;101:247–249
  9. Ten Kate J, Wijnen JT, Herbschleb-Voogt E, et al. Quantitative changes in adenosine deaminase in human colorectal adenocarcinomas. Cancer Res. 1984;44:4688–4692
  10. Camici M, Tozzi MG, Allergrini S, et al. Purine salvages enzyme activities in normal and neoplastic human tissues. Cancer Biochem Biophys. 1990;11:201–209
  11. Sanphilipo O, Camici M, Tozzi MG, et al. Relationship between the level of purine salvage pathway enzyme and clinical biological aggressiveness of human colon carcinoma. Cancer Biochem Biophys. 1994;14:57–66
  12. Sufrin G, Tritseh GL, Mittelman A, et al. Adenosine deaminase in patients with carcinoma of the bladder. J Urol. 1978;119:343–346
  13. Canbolat O, Durak I, Cetin R, et al. Activities of adenosine deaminase, 5′-nucleotidase, guanase and cytidine deaminase enzymes in cancerous and noncancerous human breast cancer. Breast Cancer Res Treat. 1996;37:189–193
  14. Namiot Z, Stasiewicz J, Namiot A, et al. Adenosine deaminase activity in patients with the intestinal type of gastric carcinoma. Cancer Lett. 1996;109:199–202
  15. Durak I, Isik AU, Canbolat O, et al. Adenosine deaminase, 5′-nucleotidase, xanthine oxidase, superoxide dismutase, and catalase activities in cancerous and noncancerous human bladder tissues. Free Rad Biol Med. 1994;16:825–831
  16. Sufrin G, Tristch GL, Mittelman A, et al. Adenosine deaminase activity in patients with renal adenocarcinoma. Cancer. 1977;40:796–802
  17. Vannoni D, Bernini A, Carlucci F, et al. Enzyme activity controlling adenosine levels in normal and neoplastic tissues. Med Oncol. 2004;21:187–195
  18. Eroglu A, Canbolat O, Demirci S, et al. Activities of adenosine deaminase and 5′-nucleotidase in cancerous and noncancerous human colorectal tissues. Med Oncol. 2000;17:319–324
  19. Bradford MM. A rapid and sensitive method for the quantitative of microgram quantities of protein utilizing the principal of protein-dye binding. Anal Biochem. 1976;72:248–254
  20. Guisti G, Galanti B. Colorimetric method. In:  Bergmeyer HU editors. Methods of Enzymatic Analysis. Weinheim: Verlag Chemie; 1984;p. 315–323
  21. Ungerer JPJ, Oosthuizen HM, Retief JH, et al. Significance of adenosine deaminase activity and its isoenzymes in tuberculous effusions. Chest. 1994;106:33–37
  22. Sari RA, Taysi S, Yilmaz O, et al. Correlation of serum levels of adenosine deaminase activity and its isoenzymes with disease activity in rheumatoid arthritis. Clin Exp Rheumatol. 2003;21:97–100
  23. Yoneyama Y, Swa R, Suzuki S, et al. Serum adenosine deaminase activity in women with hypermesis gravidrum. Clin Chem Acta. 2002;324:141–145
  24. Taysi S, Polat MF, Sari RA, et al. Serum adenosine deaminase and cytidine deaminase activities in patients with systemic lupus erythematosus. Clin Chem Lab Med. 2002;40:493–495
  25. Hitoglou S, Hatzistilianou M, Gougoutamou D, et al. Adenosine deaminase and its isoenzyme pattern in patients with juvenile rheumatoid arthritis and systemic lupus erythematosus. Clin Rheumatol. 2001;20:411–416
  26. Dornard J, Bonnafous JC, Favero J, et al. Ecto 5-nucleotidase and adenosine deaminase activities of lymphoid cells. Biochem Med. 1982;28:144–156
  27. Donofrio J, Coleman MS, Huton JJ, et al. Overproduction of adenosine deoxynucleosides and deoxynucleosine in adenosine deaminase deficiency with severe combined immunodeficiency disease. J Clin Invest. 1978;62:884–887
  28. Hersfield MS, Kredich NM. Resistance of adenosine kinase deficient human lymphoblastoid cell line to effects of deoxynucleosine on growth. S-adenosyl homocysteine hydrolase inactivation and dATP accumulation. Proc Natl Acad Sci USA. 1980;77:4292–4296
  29. Vannoni D, Bernini A, Carlucci F, et al. Enzyme activities controlling adenosine levels in normal and neoplastic tissues. Med Oncol. 2004;21:187–195
  30. Biri H, Ozturk HS, Kacmaz M, et al. Activity of DNA turnover and free radical metabolizing enzymes in cancerous human prostate tissue. Cancer Invest. 1999;17:314–319
  31. Leek RD, Harris AL. Tumor-associated macrophages in breast cancer. J Mammary Gland Biol Neoplasia. 2002;7:177–189

PII: S0188-4409(09)00201-X

doi: 10.1016/j.arcmed.2009.10.012

Archives of Medical Research
Volume 41, Issue 1 , Pages 14-18 , January 2010