Archives of Medical Research
Volume 41, Issue 1 , Pages 59-61 , January 2010

Taurine: A Potential Novel Addition to the Anti-Systemic Sclerosis Weaponry

  • Mohammad Kazem Fallahzadeh

      Affiliations

    • Shiraz Nephrourology Research Center and Dermatology Department, Shiraz University of Medical Sciences, Shiraz, Iran
    • ,
  • Mohammad Reza Namazi

      Affiliations

    • Dermatology Department and Medicinal and Natural Products Chemistry Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
    • Corresponding Author InformationAddress reprint requests to: Mohammad Reza Namazi, MD, Dermatology Department, Faghihi Hospital, Shiraz, Iran; Phone and Fax: 00987112319049
    • ,
  • Ramesh C. Gupta

      Affiliations

    • SASRD Nagaland University, Medziphema, India

Received 6 July 2009 ,Accepted 4 November 2009.

References 

  1. Denton CP. Pathogenesis of systemic sclerosis (scleroderma). Uptodate 17.1 online. 2009. [cited: May 29, 2009] Available from: http://www.uptodate.com/online/content/topic.do?topicKey=sclerode/7049&selectedTitle=2∼150&source=search_result.
  2. Yazawa N, Fujimoto M, Tamaki K. Recent advances on pathogenesis and therapies in systemic sclerosis. Clin Rev Allergy Immunol. 2007;33:107–112
  3. Bruckdorfer KR, Hillary JB, Bunce T, et al. Increased susceptibility to oxidation of low-density lipoproteins isolated from patients with systemic sclerosis. Arthritis Rheum. 1995;38:1060–1067
  4. Hussein MR, Hassan HI, Hofny ER, et al. Alterations of mononuclear inflammatory cells, CD4/CD8 + T cells, interleukin 1beta, and tumour necrosis factor alpha in the bronchoalveolar lavage fluid, peripheral blood, and skin of patients with systemic sclerosis. J Clin Pathol. 2005;58:178–184
  5. Schuller-Levis GB, Park E. Taurine and its chloramine: modulators of immunity. Neurochem Res. 2004;29:117–126
  6. Verner A, Craig S, McGuire W. Effect of taurine supplementation on growth and development in preterm or low birth weight infants. Cochrane Database Syst Rev. 2007;(4):CD006072
  7. Gray GE, Landel AM, Meguid MM. Taurine-supplemented total parenteral nutrition and taurine status of malnourished cancer patients. Nutrition. 1994;10:11–15
  8. Zhao X, Jia J, Lin Y. Taurine content in Chinese food and daily intake of Chinese men. Adv Exp Med Biol. 1998;442:501–505
  9. Rana SK, Sanders TA. Taurine concentrations in the diet, plasma, urine and breast milk of vegans compared with omnivores. Br J Nutr. 1986;56:17–27
  10. Alford C, Cox H, Wescott R. The effects of Red Bull energy drink on human performance and mood. Amino Acids. 2001;21:139–150
  11. Santangelo F. The regulation of sulphurated amino acid junctions: fact or fiction in the field of inflammation?. Amino Acids. 2002;23:359–365
  12. Cortijo J, Cerdá-Nicolás M, Serrano A, et al. Attenuation by oral N-acetylcysteine of bleomycin-induced lung injury in rats. Eur Respir J. 2001;17:1228–1235
  13. Nakajima Y, Osuka K, Seki Y, et al. Taurine reduces inflammatory responses after spinal cord injury. J Neurotrauma. 2009;[Epub ahead of print]
  14. Marcinkiewicz J, Głuszko P, Kontny E, et al. Is Taurolidine a candidate for treatment of rheumatoid arthritis?. Clin Exp Rheumatol. 2007;25:211–218
  15. Barua M, Liu Y, Quinn MR. Taurine chloramine inhibits inducible nitric oxide synthase and TNF-alpha gene expression in activated alveolar macrophages: decreased NF-kappaB activation and IkappaB kinase activity. J Immunol. 2001;167:2275–2281
  16. Schaffer SW, Azuma J, Mozaffari M. Role of antioxidant activity of taurine in diabetes. Can J Physiol Pharmacol. 2009;87:91–99
  17. Ulrich-Merzenich G, Zeitler H, Vetter H, et al. Protective effects of taurine on endothelial cells impaired by high glucose and oxidized low density lipoproteins. Eur J Nutr. 2007;46:431–438
  18. Yamamoto T, Takagawa S, Katayama I, et al. Effect of superoxide dismutase on bleomycin-induced dermal sclerosis: implications for the treatment of systemic sclerosis. J Invest Dermatol. 1999;113:843–847
  19. Chorazy M, Kontny E, Marcinkiewicz J, et al. Taurine chloramine modulates cytokine production by human peripheral blood mononuclear cells. Amino Acids. 2002;23:407–413
  20. Quinn MR, Park E, Schuller-Levis G. Taurine chloramine inhibits prostaglandin E2 production in activated RAW 264.7 cells by post-transcriptional effects on inducible cyclooxygenase expression. Immunol Lett. 1996;50:185–188
  21. Namazi MR. The beneficial and detrimental effects of linoleic acid on autoimmune disorders. Autoimmunity. 2004;37:73–57
  22. Cruz CI, Ruiz-Torres P, del Moral RG, et al. Age-related progressive renal fibrosis in rats and its prevention with ACE inhibitors and taurine. Am J Physiol Renal Physiol. 2000;278:F122–F129
  23. Shirahige A, Mizushima T, Matsushita K, et al. Oral administration of taurine improves experimental pancreatic fibrosis. J Gastroenterol Hepatol. 2008;23:321–327
  24. Gurujeyalakshmi G, Wang Y, Giri SN. Taurine and niacin block lung injury and fibrosis by down-regulating bleomycin-induced activation of transcription nuclear factor-κB in mice. J Pharmacol Exp Ther. 2000;293:82–90
  25. Miyazaki T, Karube M, Matsuzaki Y, et al. Taurine inhibits oxidative damage and prevents fibrosis in carbon tetrachloride-induced hepatic fibrosis. J Hepatol. 2005;43:117–125

PII: S0188-4409(09)00212-4

doi: 10.1016/j.arcmed.2009.11.005

Archives of Medical Research
Volume 41, Issue 1 , Pages 59-61 , January 2010

Article Tools