« Previous
Next »
Archives of Medical Research
Volume 41, Issue 2
, Pages 110-118.e2
, February 2010
Gene Expression Profiling Identifies WNT7A As a Possible Candidate Gene for Decreased Cancer Risk in Fragile X Syndrome Patients
References
- Population screening for fragile X syndrome. Lancet. 1993;341:770
- . The fragile X syndrome. In: Scriver CR, Beaudet AL, Sly WS, Valle D editor. The Metabolic Basis of Inherited Disease. 7th edn. New York: McGraw-Hill; 2001;p. 1257–1289
- . X-linked mental retardation. Med Sci Monit. 2008;14:RA221–229
- Physical mapping across the fragile X: hypermethylation and clinical expression of the fragile X syndrome. Cell. 1991;64:861–866
- Familial transmission of the FMR1 CGG repeat. Am J Hum Genet. 1996;59:1252–1261
- Fragile X permutation disorders-expanding the psychiatric perspective. J Clin Psychiatry. 2009;70:852–862
- . Chromosome fragile sites. Annu Rev Genet. 2007;41:169–192
- . Chromosomal fragile sites and cancer-specific rearrangements. Blood. 1986;67:849–858
- . Unstable triplet repeat sequences: a source of cancer mutations. Stem Cells. 1995;13:146–157
- . Demonstration of the fra(X) in lymphocytes, fibroblasts, and bone marrow in a patient with a testicular tumor. J Med Genet. 1982;20:225–227
- Fragile X syndrome and neoplasia. Am J Med Genet. 1988;30:77–82
- Brief clinical report: central nervous system neoplasm in a young man with Martin Bell syndrome-fra (X)–XLMR. Am J Med Genet. 1987;26:7–12
- . Fragile X syndrome and acute lymphoblastic leukaemia. Cancer. 1988;62:2383–2386
- Acute lymphoblastic leukemia in a patient with fragile X syndrome. Haematologica. 2003;88:ECR13
- Fragile X expression in Martin-Bell syndrome, intellectually normal individuals, and neoplasia, interpreted by a viral hypothesis. Am J Med Genet. 1988;30:697–702
- Nephroblastoma and fragile X syndrome. Arch Fr Pediatr. 1992;49:477
- Fragile X syndrome and myelodysplasia discovered during pregnancy. Br J Haematol. 1993;85:415–416
- Instability of the CGG repeat and expression of the FMR1 protein in a male fragile X patient with a lung tumor. Am J Hum Genet. 1995;57:609–618
- . The fragile X CGG repeats show a marked level of instability in hereditary non-polyposis colorectal cancer patients. Eur J Hum Genet. 1997;5:89–93
- . Nasopharyngeal carcinoma in a boy with fragile X syndrome. Pediatr Hematol Oncol. 2000;17:597–600
- . Glioblastoma in boy with fragile X: an unusual case of neuroprotection. Arch Dis Child. 2007;92:795–796
- Two boys with fragile X syndrome and hepatic tumors. J Pediatr Hematol Oncol. 2008;30:239–241
- Evidence of decreased risk of cancer in individuals with fragile X. Am J Med Genet. 2001;103:226–230
- . Cancer incidence among persons with fragile X syndrome in Finland: a population based study. J Intellect Disabil Res. 2009;53:85–90
- . A guide to fragile sites on human chromosomes. Cancer Genet Cytogenet. 1990;44:37–45
- . Significantly lower incidence of cancer among patients with Huntington disease. Cancer. 1999;86:1342–1346
- . Risk of leukaemia and solid tumors in individuals with Down's syndrome. Lancet. 2000;355:165–169
- . Macro role(s) of microRNAs in fragile X syndrome. Neuromolecular Med. 2009;(Epub ahead of print)
- . CREBa real culprit in oncogenesis. FEBS J. 2007;274:3224–3232
- . Cyclic adenosine monophosphate-dependent cell type specific modulation of mitogenic signaling by retinoids in normal and neoplastic lung cells. Cancer Detect Prev. 2006;30:403–411
- . The gene encoding the fragile X RNA binding protein is controlled by nuclear respiratory factor 2 and CREB family of transcription factors. Nucleic Acids Res. 2006;34:1205–1215
- . Ras signaling mechanisms underlaying impaired GluR1 dependent plasticity associated with fragile X syndrome. J Neurosci. 2008;28:7847–7862
- . The role of the Rho GTPases in neuronal development. Genes Dev. 2005;19:1–49
- . Deregulated Ras signaling in developmental disorders: new tricks for an old dog. Curr Opin Genet Dev. 2007;17:15–22
- . A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res. 1988;16:1214
- Methylation PCR approach for detection of fragile X syndrome. Hum Mut. 1999;14:71–79
- From genomics to chemical genomics: new developments in KEGG. Nucleic Acids Res. 2006;34:D354–357
- ALEX1, a novel human armadillo repeat protein that is expressed differentially in normal tissues and carcinomas. Biochem Biophys Res Commun. 2001;280:340–347
- . Temporal and spatial expression profile of the novel armadillo-related gene, Alex 2, during testicular differentiation in the mouse embryo. Dev Dyn. 2005;233:188–193
- The protein phosphatase 2A subunit Bgamma gene is identified to be differentially expressed in malignant melanomas by subtractive suppression hybridization. Melanoma Res. 2001;6:577–585
- A specific PP2A regulatory subunit, B56 gamma mediates DNA damage-induced dephosphorylation of p53 at Thr55. EMBO J. 2007;26:402–411
- . Expression of Wnt7a in human normal tissues and cancer, and regulation of Wnt7a and Wnt7b in human cancer. Int J Cancer. 2002;21:895–900
- Evidence that fragile X mental retardation protein is a negative regulator of translation. Hum Mol Genet. 2001;10:329–338
- Biochemical and genetic interaction between the Fragile X mental retardation protein and the microRNA's pathway. Nat Neurosci. 2004;7:113–117
- . RNA and microRNA's in fragile X mental retardation protein. Nat Cell Biol. 2004;6:1048–1053
- . A decade of molecular studies of fragile X syndrome. Annu Rev Neurosci. 2002;25:315–338
- . From mRNP trafficking to spine dysmorphogenesis: the roots of fragile X syndrome. Nat Rev Neurosci. 2005;6:376–387
- . The microRNA pathway and Fragile X mental retardation protein. Biochim Biophys Acta. 2008;1779:702–705
- Microarray identification of FMRP associated brain mRNAs and altered mRNA translational profiles in Fragile X Syndrome. Cell. 2001;107:477–487
- . Whole genome microarray analysis of gene expression in subjects with fragile X syndrome. Genet Med. 2007;9:464–472
- Functional characterization of WNT7A signaling in PC12 cells. J Biol Chem. 2003;39:37024–37031
- . Secreted frizzled-related protein 4 regulates two Wnt7a signaling pathways and inhibits proliferation in endometrial cancer cells. Mol Cancer Res. 2008;6:1017–1028
- Expression profile of Wnt molecules in leukemic cells from Iranian patients with acute myeloblastic leukemia. Iran J Immunol. 2007;3:145–154
- . Role of Wnt signaling in normal and malignant hematopoiesis. Histol Histopathol. 2006;21:761–774
- The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway. Genes Cells. 2003;8:645–654
- . Purified Wnt5a protein activates or inhibits β-catenin-TCF signaling depending on receptor context. PLoS Biol. 2006;4:570–582
- Wnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesis. BMC Immunol. 2006;29:13–29
- Restoration of Wnt-7a expression reverses non-small cell lung cancer cellular transformation through frizzled-9-mediated growth inhibition and promotion of cell differentiation. J Biol Chem. 2005;20:19625–19634
- . Mutational analyses of Wnt7a and HDAC11 as candidate tumour suppressor genes in sporadic malignant pancreatic endocrine tumours. Clin Endocrinol. 2007;66:110–114
- Characterization of Wnt7a expression in human endometrium and endometriotic lesions. Fertil Steril. 2007;6:1534–1540
PII: S0188-4409(10)00026-3
doi: 10.1016/j.arcmed.2010.03.001
© 2010 IMSS. Published by Elsevier Inc. All rights reserved.
« Previous
Next »
Archives of Medical Research
Volume 41, Issue 2
, Pages 110-118.e2
, February 2010
