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Archives of Medical Research
Volume 41, Issue 3
, Pages 154-161
, April 2010
In Vitro Modulation of Peroxisome Proliferator-activated Receptor-γ and Its Genes by C-Reactive Protein. Role of Atorvastatin
References
- . Inflammation in atherosclerosis: from vascular biology to biomarker discovery and risk prediction. Clin Chem. 2008;54:24–38
- . Atherosclerosis. The road ahead. Cell. 2001;104:503–516
- . Nuclear receptors in macrophage biology: at the crossroads of lipid metabolism and inflammation. Annu Rev Cell Dev Biol. 2004;20:455–480
- . Matrix metalloproteinases and their inhibitors in vascular remodeling and vascular disease. Biochem Pharmacol. 2008;75:346–359
- . Liver X receptor as integrator of metabolic and inflammatory signalling. J Clin Invest. 2006;116:607–614
- Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events. NEJM. 2002;347:1557–1565
- . C-reactive protein induces human peripheral blood monocytes to synthesize tissue factor. Blood. 1993;82:513–520
- . C-reactive protein stimulates MMP-1 expression in U937 histiocytes through Fc(gamma)RII and extracellular signal-regulated kinase pathway: an implication of CRP involvement in plaque destabilization. Arterioscler Thromb Vasc Biol. 2004;24:61–66
- C-reactive protein-induced up-regulation of extracellular matrix metalloproteinase inducer in macrophages: inhibitory effect of fluvastatin. Life Sci. 2006;78:1021–1028
- C-reactive protein induces endothelial cell apoptosis and matrix metalloproteinase-9 production in human mononuclear cells: implications for the destabilization of atherosclerotic plaque. Atherosclerosis. 2008;196:129–135
- . C-reactive protein (CRP) up-regulates the expression of receptor for advanced glycation end products (RAGE) and its inflammatory ligand EN-RAGE in THP-1 cells: inhibitory effects of Atorvastatin. Int J Cardiol. 2009;
- Anti-oxidative properties of fluvastatin, an HMG-CoA reductase inhibitor, contribute to prevention of atherosclerosis in cholesterol-fed rabbits. Atherosclerosis. 2001;154:87–96
- Upregulation of endothelial nitric oxide synthase by HMG CoA reductase inhibitors. Circulation. 1998;97:1129–1135
- Blum A, Shamburek R. Pleiotropic effects of statins on endothelial function, vascular inflammation, immunomodulation and thrombogenesis. Atherosclerosis doi:10.1016/j.atherosclerosis.2008.08.022
- . Lipid and non-lipid effects of statins. Hand Exp Pharmacol. 2005;170:359–382
- Effects of statins beyond lipid lowering: potential for clinical benefits. Int J Cardiol. 2006;109:7–15
- Effect of atorvastatin on in vitro expression of resistin in adipocytes and monocytes/macrophages and effect of atorvastatin treatment on serum resistin levels in patients with type 2 diabetes. Pharmacology. 2006;76:34–39
- . Atorvastatin activates PPAR-gamma and attenuates the inflammatory response in human monocytes. Inflamm Res. 2002;51:58–62
- . Genomic effect of vitamin ‘C’ and statins within human mononuclear cells involved in atherogenic process. Eur J Clin Nutr. 2005;59:978–981
- Liver X receptor-dependent repression of matrix metalloproteinase-9 expression in macrophages. JBC. 2003;278:10443–10449
- In vitro effects of atorvastatin on LPS-induced gene expression in endometriotic stromal cells. Fertil Steril. 2009;
- Induction of inflammatory gene expression by THP-1 macrophages cultured in normocholesterolemic hypertensive sera and modulatory effects of green tea polyphenols. J Hum Hypert. 2008;22:141–143
- . The role of PPARs in atherosclerosis. Trends Mol Med. 2002;8:422–430
- . Peroxisome proliferator activated receptor. How their effects on macrophages can lead to the development of new drug therapy against atherosclerosis. Anal Rev Pharmacol Toxicol. 2006;46:1–39
- . Peroxisome proliferator activated receptor in inflammation control. J Endocrinol. 2001;169:453–459
- . The C-reactive protein. J Emerg Med. 1999;17:1019–1025
- Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low density lipoprotein. PNAS. 1998;75:7614–7619
- . Feedback control of cyclooxygenase-2 expression through PPAR-γ. J Biol Chem. 2000;275:28028–28032
- C-reactive protein frequently co-localizes with the terminal complement complex in the intima of early atherosclerotic lesions of human coronary arteries. Arterioscler Thromb Vasc Biol. 1998;18:1386–1392
- Morphologic findings of coronary atherosclerotic plaques in diabetics: a postmortem study. Arterioscler Thromb Vasc Bio. 2004;24:1266–1271
- . Importance of blood cellular genomic profile in coronary heart disease. J Biomed Sci. 2006;13:17–26
- . Atorvastatin decreases lipoprotein lipase and endothelial lipase expression in human THP-1 macrophages. J Lipid Res. 2007;48:2112–2122
- . Decreased C-reactive protein-induced resistin production in human monocytes by simvastatin. Cytokine. 2007;40:201–206
- Inhibitory effect of pitavastatin (NK-104) on the C-reactive protein-induced interleukin-8 production in human aortic endothelial cells. Clin Sci. 2005;108:515–521
- MCP-1-induced enhancement of THP-1 adhesion to vascular endothelium was modulated by HMG-CoA reductase inhibitor through RhoA GTPase, but not ERK1/2-dependent pathway. Life Sci. 2004;75:1333–1341
- . Pitavastatin-induced thrombomodulin expression by endothelial cells acts via inhibition of small G proteins of the Rho family. Arterioscler Thromb Vasc Biol. 2003;23:512–517
- Multiple-dose pharmacokinetics, pharmacodynamics, and safety of atorvastatin, an inhibitor of HMG-CoA reductase, in healthy subjects. Clin Pharmacol Ther. 1996;60:687–695
- High-dose atorvastatin causes regression of endometriotic implants: a rat model. Hum Reprod. 2007;22:1474–1480
- . Modulation of COX-2 Expression by statins in human aortic smooth muscle cells: involvement of geranylgeranylated proteins. JBC. 2001;276:46849–46855
PII: S0188-4409(10)00096-2
doi: 10.1016/j.arcmed.2010.04.005
© 2010 IMSS. Published by Elsevier Inc. All rights reserved.
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Archives of Medical Research
Volume 41, Issue 3
, Pages 154-161
, April 2010
